The principle that tension stimulates collagen synthesis is explained by which law?

• A. Hooke's law
• B. Ohm's law
• C. Darcy's law
• D. Wolff's law

Answer: (D)

This item tests how tissues respond to mechanical load by remodeling. Wolff's law states that bone and other connective tissues adapt their structure and composition in response to the mechanical stresses they experience, so sustained tension can stimulate collagen production and reorganize fibers to better resist that tension. This reflects the idea that cells sense mechanical signals (mechanotransduction) and increase anabolic processes, like collagen synthesis, to reinforce the tissue where it is stressed.

The other options describe unrelated physical principles: Hooke's law deals with proportional elastic deformation of springs under load, Ohm's law relates voltage, current, and resistance in circuits, and Darcy's law describes fluid flow through porous media.